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It also rapidly induces apoptosis mediated by the release of cytochrome c via activation of c-Jun N-terminal kinase
Formula: C26H27NO5
Formula: C42H46F2N4O8
31 nM in Neuro2A cells
and phosphorylation is blocked by PP2 but not by PP3
CHM-1 icalcitol It also rapidly induces apoptosisCHM 1, a microtubule destabilizing agent, inhibits tubulin polymerization. CHM 1 is a potent and selective antimitotic antitumor activity against human hepatocellular carcinoma. CHM 1 induces growth inhibition and apoptosis via G2 M phase arrest in human hepatocellular carcinoma cells by activation of Cdc2 kinase activity. Product information CAS Number: 154554 41 3 Molecular Weight: 283. 25 Formula: C16H10FNO3 Chemical Name: 6 (2 fluorophenyl)
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